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作者讨论的重点在于反神经毒剂医学防护系统的发展,因为从医学观点来看,这类战剂造成了最大的化学威胁。沙林、塔硼、索曼、VX等神经毒剂属于抗胆碱酯酶化合物,因为它们能抑制胆碱酯酶,对胆碱酯酶的乙酰型具有最大的亲和力,人们一向认为神经毒剂毒性的主要始动因子是该酶受抑制。现有的理论认为,毒剂与乙酰胆碱酯酶结合阻碍了此酶在突触尤其是神经肌肉结点处,结束乙酰胆碱作用的正常功能。反化学战剂医学防护的进展,由于对抗胆碱酯酶
The author’s discussion focused on the development of anti-neurotoxic medical protection systems, which have posed the greatest chemical threat from a medical point of view. Sarin, tower boron, soman, VX and other nerve agents belong to the class of anticholinesterase compounds, because they inhibit the cholinesterase, the acetyl type of cholinesterase has the greatest affinity, people have always been considered nerve agent toxicity The main initiating factor is the enzyme is inhibited. The existing theory holds that the combination of a poison and acetylcholinesterase hinders the enzyme from ending its normal function of acetylcholine at synapses, especially neuromuscular junctions. Progress in anti-chemical warfare medicine protection due to antagonism of cholinesterase