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目的：建立中成药中梅片、艾片和合成冰片的鉴别方法。方法：样品经乙醚冷浸提取及ＳｅｐＰａｋＣ１８微柱处理后用手性毛细管气相色谱法进行测定。色谱条件：ＣＹＤＥＸ－Ｂ手性毛细管柱（２５ｍ×０２２ｍｍ，０２５μｍ）为分析柱，柱温１１０℃；分流进样，分流比１∶２５；进样温度２４０℃；ＦＩＤ检测器，检测器温度为３００℃；载气为高纯氮气，柱压１１３ｋＰａ；燃气为氢气，流速３８ｍＬ·ｍｉｎ－１；助燃气为空气，流速４００ｍＬ·ｍｉｎ－１。结果：发现这３种标示含梅片的中成药（桂林西瓜霜喷剂、双料喉风散和八宝惊风散）均未用梅片投料。结论：本法可作为中成药中梅片、艾片和合成冰片的鉴别方法。
Objective: To establish the identification method of Chinese patent medicines, such as plum, wormwood and synthetic borneol. Methods: Samples were extracted by ethyl ether cold extraction and treated with Sep-Pak C18 microcolumn and analyzed by chiral capillary gas chromatography. Chromatographic conditions: CYDEX-B chiral capillary column (25m×022mm, 025μm) as analytical column, column temperature 110°C; split injection, split ratio 1:25; injection temperature 240°C; FID detector, The detector temperature is 300°C; the carrier gas is high purity nitrogen, the column pressure is 113kPa; the gas is hydrogen, the flow rate is 38mL·min-1; the combustion gas is air, and the flow rate is 400mL·min-1. RESULTS: It was found that the three proprietary Chinese medicines (Guilin watermelon cream spray, Shuangliu throat wind powder, and Babao scare powder) marked with plum tablets were not fed with plum paste. Conclusion: This method can be used as a discriminating method for Chinese patent medicines such as plum, wormwood and synthetic borneol.