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目的探讨卡托普利联合川芎嗪治疗急性肾小球肾炎的疗效。方法将2009年1月-2011年12月期间我科收治的急性肾小球肾炎患者110例随机分为观察组与对照组各55例,观察组在常规治疗的基础上加用卡托普利联合川芎嗪,对照组仅接受常规治疗,比较两组患者的疗效。结果观察组肉眼血尿消失时间、水肿消退时间、血压恢复正常时间显著短于对照组,两组比较差异有统计学意义(P<0.05)。治疗后,观察组血尿转阴率显著高于对照组,两组比较差异有统计学意义(P<0.05)。结论卡托普利联合川芎嗪治疗急性肾小球肾炎具有疗效好、恢复快等优点。
Objective To investigate the curative effect of captopril and ligustrazine on acute glomerulonephritis. Methods 110 patients with acute glomerulonephritis treated in our department from January 2009 to December 2011 were randomly divided into observation group and control group (n = 55). The observation group was treated with captopril Combined with ligustrazine, the control group received only routine treatment, the efficacy of the two groups were compared. Results The gross hematuria disappear time, edema subsidence time and blood pressure recovery time in the observation group were significantly shorter than those in the control group. The differences between the two groups were statistically significant (P <0.05). After treatment, the hematuria negative rate in the observation group was significantly higher than that in the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion Captopril combined with ligustrazine in the treatment of acute glomerulonephritis has the advantages of good curative effect and rapid recovery.