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目的 :探讨早期干预对新生儿缺氧缺血性脑病 (HIE)预后的作用。方法 :将 3 5 2例中、重度HIE患儿随机分为两组 :①对照组 :172例接受HIE常规支持、对症等治疗 ;②干预组 :180例在HIE常规支持、对症等治疗的基础上予以高压氧、视觉刺激、听觉刺激、触觉刺激、语言刺激、运动训练及刺激、经络导频、静滴丽珠赛乐 (或脑活素 )等早期干预措施 ,4～ 6个疗程甚至更长。对比两组患儿智力、运动发育状况及继发性癫痫、脑瘫发生情况。结果 :干预组智能低下、运动发育迟缓、继发性癫痫 ,脑瘫发生率明显低于对照组 ,差异有显著性 ,P <0 0 1。结论 :对HIE进行早期干预能显著减少的发生 ,明显改善其预后
Objective: To investigate the effect of early intervention on the prognosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods: A total of 352 children with moderate and severe HIE were randomly divided into two groups: ① control group: 172 patients received routine HIE support and symptomatic treatment; ② The intervention group: 180 patients underwent routine HIE support and symptomatic treatment 4 to 6 courses or even more interventions such as hyperbaric oxygen, visual stimulation, auditory stimulation, tactile stimulation, verbal stimulation, exercise training and stimulation, meridian pilot, intravenous injection of Cristallo (or cerebrolysin) long. Compare the two groups of children with mental, motor development and secondary epilepsy, cerebral palsy occurred. Results: The incidence of mental retardation, motor retardation, secondary epilepsy and cerebral palsy in the intervention group was significantly lower than that in the control group, the difference was significant (P <0.01). Conclusion: The early intervention of HIE can significantly reduce the incidence, significantly improve their prognosis