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目的：探讨颅内肿瘤切除术后颅内感染危险因素。方法回顾性分析126例颅内肿瘤切除患者临床资料,总结术后颅内感染危险因素及预防对策。结果手术时间≥4h患者感染率大于手术时间＜4h的患者,P＜0.05；伴有脑脊液漏患者感染率明显高于无脑脊液漏患者, P＜0.05；引流留置时间≥24h患者感染率高于引流留置时间＜24h的患者,P＜0.05。结论手术时间、脑脊液漏及引流留置时间等因素是出现颅内感染的主要危险因素,须得到临床重视,加强预防。“,”Purpose: objective to explore the risk factors of intracranial infection after intracranial tumor resection. Methods retrospective analysis 126 cases of intracranial tumor resection in patients with clinical data,summarizes the risk factors of postoperative intracranial infection and prevention countermeasures. Results operation time 4 h or higher infection rate is greater than the operation time patients <4h patients,P<0.05; Accompanied by infection rates were significantly higher than those without a CSF leakage of cerebrospinal fluid leakage patients,P<0.05; Drainage in patients with indweling time of 24 h or higher infection rate is higher than the drainage of indweling time < 24 h patients,P<0.05. Conclusion operative time, drainage of cerebrospinal fluid leakage and such factors as the indweling time is a major risk factors of intracranial infection, must get clinical attention, strengthen prevention.