女阴派杰氏病—附11例分析

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女阴派杰氏病为外阴原位癌的一种特殊形态,病灶呈鲜红色,边界清楚,表面粗糙略突起,有时见小颗粒或浅溃疡,时有渗液,长期瘙痒,颇似湿疹,又称女阴湿疹样癌。在镜下可见大块派杰氏细胞,与乳头部派杰氏病相同,故亦称乳房外派杰氏病。本文就11例女阴派杰氏病进行回顾性临床病理分析,以探讨其组织发生及诊治方法。资料分析女阴癌为妇科恶性肿瘤之一,其发生率仅次于宫颈癌、宫体癌、卵巢癌而占女性生殖器恶性肿瘤的第四位。本院1953年1月至1987年6月共收治女阴癌179例,同时有11例女阴派杰氏病,其发生率为女阴癌的6.1%,较Taylor 报告的1.9%为高。一、一般资料:年龄:33~73岁,平均61.2岁,>60岁者占72.7%。婚育:均已婚及已育。与月经关系:本病发生在绝经期前3例,绝经后8例,且发生在绝经后8~25年。二,症状及体征:主要症状是长期外阴瘙痒(10例),因抓痒使表面溃破、渗液及疼痛。仅1例主诉外阴色素减退。病灶分布范围较广,常累及大小阴唇、阴蒂等,表面粗糙,潮红,边界清楚,有时糜烂、溃疡、湿润;在病灶区常伴有色素减退区。少数 Female genital Jake’s disease is a special form of vulvar carcinoma in situ, the lesion was bright red, the border is clear, the surface roughness slightly protruding, sometimes see small particles or shallow ulcers, sometimes exudate, long-term itching, quite like eczema, Also known as eczema-like cancer. Seen in the microscope chunks sent Jieshi cells, and the Ministry of the nipple sent Jieshi same, it is also known as outside the breast Jie Jieshi. In this paper, 11 cases of female Jyuddy’s disease were retrospectively analyzed clinically and pathologically in order to explore its organization and diagnosis and treatment methods. Data analysis Female cancer is one of gynecological malignancies, the incidence of second only to cervical cancer, uterine cancer, ovarian cancer and female genital malignancies fourth. Our hospital from January 1953 to June 1987 admitted a total of 179 cases of female cancer of the vagina, and at the same time there were 11 cases of Jieshi disease, the incidence of female cancer was 6.1%, compared with Taylor 1.9% is high. First, the general information: Age: 33 ~ 73 years old, average 61.2 years old,> 60 years old accounted for 72.7%. Marriage and childcare: both married and already educated. Relationship with menstruation: The disease occurred in 3 cases before menopause, 8 cases after menopause, and occurred in 8 to 25 years after menopause. Second, the symptoms and signs: The main symptoms are long-term genital itching (10 cases), due to scratching the surface ulceration, exudate and pain. Only 1 case complained of decreased vaginal pigment. Lesions spread over a wide range, often involving the size of the labia, clitoris, etc., the surface roughness, flushing, clear boundaries, sometimes erosion, ulcers, moist; often accompanied by hypopigmentation in the lesion area. few
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