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目的 观察香姑多糖 (LNT)腔内注射治疗恶性胸腔积液的效果。方法 对 5 2例恶性胸腔积液病人 ,腔内注射LNT4mg～ 6mg ,观察有效率、副反应。结果 LNT腔内注射的有效率为 65 3 % ,副反应为发热和胸痛 ,分别为 5 8%和 3 8%。5 0 %病人KPS评分增高 ,中位缓解期 4 1个月 ,中位生存期 6个月。结论 胸腔注射LNT对恶性胸腔积液有良好疗效 ,副反应轻。适用于年老体弱 ,全身状况较差的恶性胸腔积液病人的胸腔内局部治疗
Objective To observe the effect of intracavitary injection of saffron (LNT) in the treatment of malignant pleural effusion. Methods 52 cases of malignant pleural effusion patients, intraluminal injection of LNT4mg ~ 6mg, observe the efficiency, side effects. Results The effective rate of intracavitary injection of LNT was 65.3%. The side effects were fever and chest pain, which were 58% and 38% respectively. 50% of patients KPS score increased, the median remission 4 1 months, the median survival of 6 months. Conclusions Thoracic injection of LNT has a good curative effect on malignant pleural effusion with mild side effects. For frail elderly, poor general condition of malignant pleural effusion in patients with intrathoracic local treatment