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目的研究乌司他丁治疗严重多发伤的临床价值。方法将64例严重多发伤患者随机分为治疗组(32例)和对照组(32例)。治疗组患者在常规治疗的基础上,自入院当天开始静脉滴注乌司他丁(UTI),对照组患者只给予常规治疗。结果两组患者平均住ICU时间、平均住院时间和多器官功能障碍综合征(MODS)发生率间差异均有统计学意义(P<0.05)。结论乌司他丁能抑制多发伤患者炎症反应,保护重要脏器功能,减少MODS的发生。
Objective To study the clinical value of ulinastatin in the treatment of severe multiple trauma. Methods 64 patients with severe multiple trauma were randomly divided into treatment group (32 cases) and control group (32 cases). On the basis of routine treatment, the patients in the treatment group were given intravenous ulinastatin (UTI) on the day of admission and the patients in the control group were given routine treatment only. Results The mean ICU stay, average length of stay, and multiple organ dysfunction syndrome (MODS) between the two groups were statistically significant (P <0.05). Conclusion Ulinastatin can inhibit inflammation in patients with multiple trauma, protect the function of vital organs and reduce the incidence of MODS.