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目的对经外周静脉置入中心静脉导管(PICC)术后深静脉血栓(DVT)发生规律进行相关探讨,同时探究低相对分子质量肝素(LMWH)对肿瘤患者PICC置管后深静脉血栓的预防效果。方法选择2014年3月至2016年10月期间600例PICC置管术后患者DVT的发生情况进行统计分析,并统计观察期间PICC置管术后发生DVT的患者使用LMWH并进行护理干预后深静脉血栓复发情况,将同期PICC置管术后未应用LMWH的患者设为对照组,并进行比较。结果 PICC置管术后DVT发生率为7.00%,其与伴糖尿病或高血压、冠心病、感染、长期卧床、D二聚体增高有明显的关系;应用LMWH后,PICC置管术后发生DVT的患者深静脉血栓发生率为0.00%,PICC置管术后未应用过LMWH的患者DVT发生率为7.00%,差异显著(P<0.05)。结论肿瘤患者PICC置管后发生DVT概率较高,其与伴糖尿病或高血压、冠心病、感染、长期卧床、D二聚体增高有明显的关系;通过LMWH的使用以及积极的护理干预能对DVT的发生率进行显著的减少,同时具有很高的安全性。
Objective To investigate the incidence of deep venous thrombosis (DVT) after peripheral vein catheterization (PICC) and to explore the preventive effect of low molecular weight heparin (LMWH) on deep venous thrombosis after PICC catheterization in cancer patients . Methods The incidence of DVT in 600 patients with PICC during catheterization between March 2014 and October 2016 was statistically analyzed. During the observation period, patients with DVT after PICC catheterization were treated with LMWH and received deep nursing intervention Thrombosis relapse, the same period PICC catheterization without LMWH patients as a control group, and compared. Results The incidence of DVT after PICC catheterization was 7.00%, which was significantly associated with diabetes mellitus or hypertension, coronary heart disease, infection, prolonged bed rest and increased D-dimer. After LMWH, DVT occurred after catheterization Of patients with DVT was 0.00%. The incidence of DVT was 7.00% in patients without LMWH after PICC catheterization (P <0.05). Conclusion The incidence of DVT after PICC catheterization in cancer patients is higher, which is obviously related to the increase of diabetes, high blood pressure, coronary heart disease, infection, prolonged bed rest and D-dimer. Through the use of LMWH and positive nursing intervention, Significantly reduce the incidence of DVT, at the same time with high security.