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80例经直肠(90m)~Tc-MIBI 测定结果显示,心肝核素显影比值(H/L)在正常对照组(15例)为0.267±0.1,病毒性肝炎组(8例)轻度升高(0.455±0.13),肝硬化组(57例)显著升高。其中Child-Pugh A 级患者的 H/L 为0.57±0.12,B 级1.0±0.19,C 级1.19±0.25,提示 H/L 与 Child-Pugh 分级呈趋势相关(P<0.0)。13例在手术时测定的门静脉压力与 H/L 呈显著相关(r=0.87,P<0.01)从公式 Y=6.77+32.5 H/L 可以推算出门静脉压力。以 H/L≥0.62为阳性,诊断肝硬化门脉高压的敏感度96%,特异度89%,准确率94%。提示经直肠(99m)~Tc-MIBI 测定是无创伤诊断门脉高压的可靠安全的新手段。
The results of 80 cases of rectal (90m) ~ Tc-MIBI showed that the H / L ratio was 0.267 ± 0.1 in the normal control group (15 cases) and slightly increased in the viral hepatitis group (8 cases) (0.455 ± 0.13), cirrhosis group (57 cases) increased significantly. Among them, Child-Pugh class A patients had a H / L of 0.57 ± 0.12, a B level of 1.0 ± 0.19 and a C level of 1.19 ± 0.25, suggesting a trend-related trend of H / L and Child-Pugh classification (P <0.0). Portal pressure was significantly correlated with H / L in 13 patients (r = 0.87, P <0.01). The portal pressure was calculated from the formula Y = 6.77 + 32.5 H / L. To H / L ≥ 0.62 as positive, the diagnosis of cirrhosis and portal hypertension sensitivity 96%, specificity 89%, accuracy 94%. It is suggested that the transrectal (99m) ~ Tc-MIBI assay is a new method for the non-invasive diagnosis of portal hypertension.