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目的评价抗PPD－IgG检测对活动性肺结核的诊断价值。方法采用快速酶联免疫吸附法(ELISA)检测340例活动性肺结核、56例非活动性肺结核、88例非结核性病人血清中的抗PPD－IgG。结果活动性肺结核组抗PPD－IgG阳性率为83．8％,其中痰涂片(＋)组为92．2％,涂片(－)组为78．7％。非活动性肺结核组3例阳性,非结核组5例阳性,假阳性率分别为7．1％和5．7％。本法敏感性为83．8％,特异性为93．8％,准确性为86．8％,阳性预测值为96．9％,阴性预测值71．1％。结论。提示血清抗PPD－IgG测定是肺结核病人一项有用的辅助诊断手段。
Objective To evaluate the diagnostic value of anti-PPD-IgG for active pulmonary tuberculosis. Methods Rapid anti-PPD-IgG was detected in 340 cases of active pulmonary tuberculosis, 56 cases of non-active pulmonary tuberculosis and 88 cases of non-tuberculous patients by rapid enzyme-linked immunosorbent assay (ELISA). Results The positive rate of anti-PPD-IgG in active tuberculosis group was 83.8%, of which 92.2% in sputum smear (+) group and 78.7% in smear (-) group. In 3 cases of non-active pulmonary tuberculosis group, 5 cases were positive and non-tuberculosis group was positive, the false-positive rates were 7.1% and 5.7% respectively. The sensitivity of this method was 83.8%, the specificity was 93.8%, the accuracy was 86.8%, the positive predictive value was 96.9% and the negative predictive value was 71.1%. in conclusion. Tip serum anti-PPD-IgG determination of tuberculosis patients is a useful diagnostic tool.