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目的应用美罗华治疗血小板(PLT)输注无效的患者。方法在患者 PLT 输注的同时给予美罗华375 mg/m~2加入5%生理盐水500 mL 中静滴,监测患者外周血 PLT 计数。结果患者24 h 后测外周血 PLT 为84 × 10~9/L,48 h为63×10~9/L,72 h 为42×10~9/L,之后一直维持在30×10~9/L 以上,基础疾病也逐渐好转。结论美罗华可能是治疗 PLT 输注无效的一种较好选择。
Objective To apply rituximab to treat patients with impaired platelet transfusion (PLT). Methods In patients with PLT infusion while giving Rituximab 375 mg / m 2 added 5% saline 500 mL intravenous infusion, monitoring of peripheral blood PLT count. Results After 24 h, PLT was 84 × 10 ~ 9 / L in peripheral blood, 63 × 10 ~ 9 / L in 48 h, 42 × 10 ~ 9 / L in 72 h, and 30 × 10 ~ 9 / L above, the underlying disease is gradually improved. Conclusion Rituximab may be a better choice for the treatment of ineffective PLT infusion.