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目的探讨2型糖尿病合并冠心病患者冠状动脉造影及眼底荧光血管造影的特点。方法对203例2型糖尿病合并冠心病患者的冠状动脉造影及眼底荧光血管造影结果,按照不同年龄或总胆固醇(TC)分组进行对比分析,并应用多因素logistic回归分析探讨影响血管造影特点的危险因素。结果不同年龄组之间随着年龄的增长,冠状动脉的单支血管病变比例降低,三支血管病变及左主干受累比例增高,视网膜病变亦增多并趋于严重,而其在TC异常组与TC正常组之间的差别无统计学意义；Logistic回归分析显示冠状动脉的病变程度与血糖、年龄、甘油三酯、性别等因素相关,视网膜病变程度与血糖和年龄相关。结论不同年龄组2型糖尿病合并冠心病患者的血管造影结果存在明显差异,年龄的增长能同时加重2型糖尿病合并冠心病患者的冠状动脉病变和视网膜病变。
Objective To investigate the characteristics of coronary angiography and fundus fluorescein angiography in type 2 diabetic patients with coronary heart disease. Methods The results of coronary angiography and fundus fluorescein angiography in 203 patients with type 2 diabetes mellitus complicated with coronary heart disease were analyzed according to different ages or total cholesterol (TC) group, and multivariate logistic regression analysis was used to explore the risk of affecting the characteristics of angiography factor. Results As age increased, the proportion of single vessel lesion in coronary arteries decreased, the proportion of three vessel lesion and left main stem increased, retinopathy also increased and tended to be serious. However, Logistic regression analysis showed that the severity of coronary artery disease was related to the factors such as blood glucose, age, triglyceride and sex, and the degree of retinopathy was related to blood glucose and age. Conclusion Angiography results of patients with type 2 diabetes mellitus and coronary heart disease in different age groups have obvious difference. The increase of age can aggravate coronary artery disease and retinopathy in patients with type 2 diabetes mellitus complicated with coronary heart disease.