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目的观察乌司他丁治疗急性肺损伤患者的效果。方法将息县妇幼保健院收治的56例急性肺损伤患者随机分为治疗组及乌司他丁治疗组和对照组,对照组接受常规治疗,治疗组在对照组的基础上加用乌司他丁。对比分析两组的临床疗效。结果乌司他丁在呼吸频率、PaO2、PaCO2与PaO2/FiO2、二氧化碳结合力、C-反应蛋白(CRP)、丙二醛、超氧化物歧化酶以及谷胱甘肽过氧化物酶,九项指标均比比对照组治疗后效果更加显著P<0.05。结论乌司他丁可显著改善呼吸频率、PaO2、PaCO2与PaO2/FiO2,对急性肺损伤早期应用治疗效果明显。
Objective To observe the effect of ulinastatin in patients with acute lung injury. Methods Fifty-six patients with acute lung injury admitted to MCH county were randomly divided into treatment group and ulinastatin group and control group. The control group received routine treatment. The treatment group was treated with ulinastat Ding. Comparative analysis of two groups of clinical efficacy. Results Ulinastatin had no significant difference in respiratory rate, PaO2, PaCO2 and PaO2 / FiO2, carbon dioxide binding capacity, C-reactive protein (CRP), malondialdehyde, superoxide dismutase and glutathione peroxidase The indexes were more significant than those of the control group after treatment (P <0.05). Conclusion Ulinastatin can significantly improve the respiratory rate, PaO2, PaCO2 and PaO2 / FiO2, acute lung injury early application of treatment effect is obvious.