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2000年美国55200人死于癌症,其中约9％～11％死于大肠癌,大肠癌占美国癌症死因第二位。近段大肠癌多见于年轻人(<50岁)、女性、老年人(>80岁)、且有家族史者。其与并存病的关系尚未广泛研究。研究者假设老年、女性及伴有并存病与近段大肠癌有关联,并进行调查验证。 方法:从佛罗里达州癌肿资料系统确定1994年发生9550例大肠癌,剔除肛管肿瘤。将大肠癌分成近段(盲肠、升结肠及横结肠)和远段(降结肠、乙状结肠及直肠)。按诊断时情况确定病期,早期指Ⅰ、Ⅱ期,晚期指Ⅲ、Ⅳ期。用于多变量分析的变量还有保险支付者、种族、婚姻状态和并存病(心梗、充血性心衰、周边血管病、脑血管病、痴呆、慢性肺病、糖尿
In 2000, 55,200 Americans died of cancer, of which about 9% to 11% died of colorectal cancer. Colorectal cancer accounts for the second leading cause of cancer in the United States. Colorectal cancer more common in young people (<50 years old), women, the elderly (> 80 years), and family history. Its relationship with coexisting disease has not been extensively studied. The researchers hypothesized that the elderly, women and associated comorbidities associated with proximal colorectal cancer, and conduct investigation and verification. Methods: According to the Florida Cancer Information System, 9550 colorectal cancers were detected in 1994 and the tumors of the anal canal were removed. Colon cancer is divided into proximal (cecum, ascending colon and transverse colon) and distal (descending colon, sigmoid and rectum). According to the diagnosis of the disease stage, early refers to Ⅰ, Ⅱ, late refers to Ⅲ, Ⅳ period. Variables used for multivariate analysis included insurance payer, race, marital status and comorbid conditions (MI, congestive heart failure, peripheral vascular disease, cerebrovascular disease, dementia, chronic lung disease, diabetes