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[目的 ]开展疫情监测和媒介调查 ,防止登革热暴发流行。 [方法 ]采集可疑病人双份血清、不明原因发热病人和健康人静脉血 ,以血凝抑制和免疫萤光法检测 Ig M和 Ig G;以房屋指数、容器指数和布雷图指数确定媒介种群密度。[结果 ]1999年原流行区发现可疑病人 3例 ,Ig G阳性 1例 ,患者系境外感染 ;福州、漳州不明原因发热 73例 ,Ig M和 Ig G抗体均为阴性 ;以免疫萤光法检测 1999年流行区健康人群血清 10 0份 ,Ig G阳性率为 17.0 % ,其它地区 2 5 0份均为阴性。11个县 (市、区 ) 38个媒介调查点仅捕获白纹伊蚊 ,其幼虫密度平均房屋指数 37.3% ,容器指数 4 5 .0 % ,布雷图指数78.9;沿海地区白纹伊蚊密度远较山区县为高。白纹伊蚊各类孳生环境多达 2 7种。[结论 ]登革热在福建沿海地区存在流行的危险性。
[Objective] To carry out epidemic situation monitoring and media investigation to prevent the outbreak of dengue fever. [Methods] Twelve serums of suspicious patients, venous blood of patients with fever of unknown cause and healthy people were collected. IgM and IgG were detected by hemagglutination inhibition and immunofluorescence method. The density of media population was determined by housing index, container index and Brett index . [Results] Three cases of suspected patients were found in the original epidemic area in 1999, Ig G was positive in 1 case. The patients were out of the country. 73 cases of unexplained fever in Fuzhou and Zhangzhou were negative, Ig M and Ig G antibodies were negative. Immunofluorescence assay In 1999, the prevalence of serum IgE in healthy population was 100, the positive rate of Ig G was 17.0%, and the other 50 cases were negative. Aedes albopictus was captured at 38 media in 11 counties (cities and districts) with average larval density of 37.3%, container index of 45.0% and Bretton index of 78.9. The density of Aedes albopictus in coastal areas was far Higher than the mountainous area. Aedes albopictus all kinds of breeding environment up to 27 species. [Conclusion] Dengue fever has epidemic risk in the coastal area of Fujian.