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对接受三联免疫抑制治疗（环孢素＋硫唑嘌呤＋皮质激素）的连续１４５例尸体肾移植中，发现２８例耐激素排斥反应，其中２２例应用抗Ｔ细胞球蛋白（ＡＴＧ）治疗。ＡＴＧ２～４ｍｇ／（ｋｇ·ｄ）加入２５０ｍｌ生理盐水于８ｈ内缓慢静滴３～６ｄ，其中１８例肾功能恢复正常。这些患者平均血肌酐由治疗前的５１．５ｍｇ／Ｌ降至２１．０ｍｇ／Ｌ，６个月后维持在１９．８ｍｇ／Ｌ。一年移植肾成活率为８３．３％，而同期急性排斥反应应用激素逆转排斥反应患者为８６％。显示ＡＴＧ治疗耐激素排斥反应有效，可以使有耐激素排斥反应的肾移植患者获得极好的肾功能。
Of 145 consecutive cadaveric kidney transplant recipients receiving triple immunosuppressive therapy (cyclosporine + azathioprine + corticosteroids), 28 were found to have hormone-refractory responses, 22 of whom were treated with anti-T-globulin (ATG). ATG2 ~ 4mg / (kg · d) by adding 250ml normal saline drip 8h slow intravenous 3 ~ 6d, of which 18 cases of renal function returned to normal. The average serum creatinine in these patients dropped from 51.5 mg / L before treatment to 21.0 mg / L and remained at 19.8 mg / L after 6 months. One year graft survival rate was 83.3%, while the same period the application of acute rejection rejection hormone response was 86%. This shows that ATG is effective in treating hormone-refractory rejection and can obtain excellent renal function in renal transplant patients with hormone-refractory response.