论文部分内容阅读
丁胺卡那霉素是一种新的半合成氨基糖苷类抗生素,其最重要的特点是对其他氨基糖苷类抗生素耐药的革兰氏阴性杆菌,包括绿脓杆菌感染有效。国产丁胺卡那霉素已由四川抗菌素工业研究所及成都制药四厂研试成功,本文报道临床病人肌注国产丁胺卡那霉素连续3天的血药浓度和药代动力学的研究结果。 选择感染患者7例,平均年龄35岁,其中脓性胆管炎1例,右肺脓肿1例,阑尾炎穿孔伴急性腹膜炎4例,慢性支气管炎急性发作伴肺心病1例。这些患者中,前6例
Amikacin is a new semi-synthetic aminoglycoside antibiotic whose most important feature is effective against Gram-negative bacilli, including Pseudomonas aeruginosa, that are resistant to other aminoglycoside antibiotics. Domestic amikacin has been successfully researched by Sichuan Institute of Antibiotics and Chengdu No.4 Pharmaceutical Factory. This article reports the plasma concentrations and pharmacokinetics of domestic amikacin for 3 consecutive days in clinical patients result. Infected patients were selected in 7 cases, with an average age of 35 years old, including 1 cases of purulent cholangitis, 1 case of right lung abscess, 4 cases of appendicitis perforated with acute peritonitis, and 1 case of chronic bronchitis with pulmonary heart disease. Among these patients, the first 6 cases