大肠癌肝转移的射频消融治疗

• 作 者: 范卫君 张亮 顾仰葵 张福君 黄金华 李传行 赵明 肖鹏 吴沛宏
• 机 构: 华南肿瘤学国家重点实验室 中山大学附属肿瘤医院影像介入中心,华南肿瘤学国家重点实验室,中山大学附属肿瘤医院影像介入中心,华南肿瘤学国家重点实验室,中山大学附属肿瘤医院影像介入中心,华南肿瘤学国家重点实
• 出 处: 介入放射学杂志
• 发表日期: 2006年02期
• 关键词: 大肠癌肝转移 射频消融 肿瘤治疗效果 治疗仪 肝转移 坏死者 双期增强扫描 实质脏器肿瘤 小瘤 肝脏肿瘤

目的研究大肠癌肝转移射频消融(RFA)治疗近期局部疗效和不良反应。方法大肠癌肝转移患者32例,病灶总数71个,其中直径小于4.0 cm的病灶41个,4.1~5.0 cm者14个,5.1~6.0 cm者9个,大于6.1 cm者7个。经RFA治疗1个月后行螺旋CT双期增强扫描评价肿瘤治疗效果。结果不同大小瘤灶经消融治疗后达到完全坏死者分别为41个(41/41),13个(13/14),4个(4/9),2个(2/7)。无严重不良反应和并发症。结论RFA安全可靠,不良反应小,是治疗大肠癌肝转移的有效方法之一。

Objective To study the recent local efficacy and adverse reactions of radiofrequency ablation of liver metastasis of colorectal cancer (RFA). Methods Totally 32 patients with liver metastases from colorectal cancer were enrolled. There were 71 lesions, of which 41 lesions were smaller than 4.0 cm in diameter, 14 in 4.1 ~ 5.0 cm, 9 in 5.1 ~ 6.0 cm, and 7 in more than 6.1 cm. One month after the RFA treatment, the spiral CT double-phase enhanced scan was used to evaluate the effect of tumor therapy. Results Totally 41 (41/41), 13 (13/14), 4 (4/9) and 2 (2/7) patients achieved complete necrosis after ablation. No serious adverse reactions and complications. Conclusions RFA is safe and reliable with small adverse reactions and is an effective method for the treatment of liver metastasis of colorectal cancer.