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乙胺丁醇作为抗痨药物于1961年问世。由于其毒性小、效果好,应用日趋广泛。但由服用乙胺丁醇引起失明的病例已屡见不鲜,引起临床重视。据报告,目前应用的D型异构体,尽管毒性和用量都有所减少,但视力损害仍可达1％～8％左右。乙胺丁醇引起的视力损害临床上可分为两种类型;一是中央型。临床表现为视力下降,视物模糊,中心暗点,红绿色弱。二是周围型。表现为视野狭窄。乙胺丁醇引起的视力损害多发生在服药后
Ethambutol came out in 1961 as an anti-tuberculosis drug. Because of its toxicity, the effect is good, the application is more extensive. However, the cases of blindness caused by taking ethambutol have been uncommon, causing clinical attention. It is reported that currently used D-isomer, although the toxicity and dosage are reduced, but the visual impairment can still reach 1% to 8%. Ethambutol caused by visual impairment can be divided into two types of clinics; First, the central type. Clinical manifestations of vision loss, blurred vision, the center of dark spots, red and green weak. Second, the surrounding type. Performance for the narrow field of vision. Ethambutol caused by visual impairment occurred more often after taking the drug