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目的:探讨溴隐亭联合克罗米芬在催乳素(PRL)水平正常的排卵障碍患者中的促排卵治疗效果。方法:选择血清PRL水平正常的排卵障碍患者96例,随机分为对照组(n=56,仅常规给予克罗米芬)和研究组(n=40,除常规给予克罗米芬外加用溴隐亭),比较两者的促排卵效果。结果:对照组的成熟卵泡排卵率及临床妊娠率分别为71.7%(99/138)和28.6%(16/56),研究组为88.3%(91/103)和47.5%(19/40),研究组显著高于对照组(P<0.05)。结论:克罗米芬联合溴隐亭可以作为一种有效的促排卵方案用于治疗催乳素水平正常的排卵障碍患者,以促进卵泡发育并提高妊娠率。
Objective: To investigate the ovulation induction treatment of bromocriptine combined with clomiphene in patients with normal ovulation disorder (PRL). Methods: Ninety-six patients with ovulation disorder with normal serum PRL levels were randomly divided into control group (clomiphene citrate only) and study group (n = 40, except clomiphene plus bromocriptine) Compare the two ovulation promoting effect. Results: The ovulation rate and clinical pregnancy rate of mature follicles in control group were 71.7% (99/138) and 28.6% (16/56), respectively. The study group was 88.3% (91/103) and 47.5% (19/40) The study group was significantly higher than the control group (P <0.05). Conclusion: Clomiphene combined with bromocriptine can be used as an effective ovulation induction regimen in the treatment of patients with ovulation disorders with normal prolactin levels to promote follicular development and improve pregnancy rate.