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多发性硬化(MS)可导致勃起功能障碍(ED),枸橼酸西地那非对于此类患者的治疗效果怎样呢?Fowler CJ等人进行了相关研究。一共有217个患者接受了西地那非(25～100mg；n=104)或者安慰剂(n=113)治疗,为期12周。疗效根据国际勃起功能指数问卷(IIEF)中的获得勃起(Q3)和维持勃起(Q4)问题,以及总评题(GEQ)进行评价,同时也评估生活质量。12周后,西地那非组的IIEF Q3和Q4的平均分值比安慰剂组高(P＜0．0001),西地那非组有89%(92/103)的患者报
Multiple sclerosis (MS) can lead to erectile dysfunction (ED), sildenafil citrate for the treatment of such patients what effect? Fowler CJ et al were related studies. A total of 217 patients received sildenafil (25-100 mg; n = 104) or placebo (n = 113) for 12 weeks. Efficacy was assessed according to the erectile (Q3) and maintenance erection (Q4) questions in the IIEF, as well as the General Question Question (GEQ), as well as the quality of life. After 12 weeks, mean scores for IIEF Q3 and Q4 in the sildenafil group were higher (P <0.0001) than those in the placebo group and 89% (92/103) in the sildenafil group