Bifunctional catalysis of Morita-Baylis-Hillman (MBH) reaction with chiral primary-tertiary diamine:

• 作 者: Long Zhang (1) SanZhong Luo
• 机 构: 1.DepartmentofChemistryandStateKeyLaboratoryofElemento-OrganicChemistry,2.BeijingNationalLaboratoryf
• 出 处: 中国科学：化学英文版
• 发表日期: 2009年9期
• 关键词: Morita-Baylis-Hillman REACTION primary amine ENAMINE IMINIUM organocatalyst Mori
• 基金项目: Supported by the National Natural Science Foundation of China (Grant Nos. 20421202, 20632060 and 20702052),Ministry of Science and Technology of China (Grant No. 2008CB617501 & 2009ZX09501-018), a

A simple primary-tertiary diamine has been explored as a novel catalyst for the Morita-Baylis-Hillman reaction of MVK and aryl aldehydes, and moderate to good chemical yields were obtained. Detailed mechanism study indicated that the diamine acted as a bi