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肿瘤免疫逃疫的机制之一是肿瘤能够诱导免疫抑制性细胞产生,包括髓系抑制性细胞(myeloid suppressor cells,MSCs)和调节性T细胞(regulatory Tcells,T-regs)等,但是这两类细胞之间是否存在直接的相互作用尚不清楚。早在20世纪80年代,人们就发现肿瘤患者和荷瘤小鼠体内有MSCs聚积
One of the mechanisms of tumor immune escape is that tumor can induce the production of immunosuppressive cells, including myeloid suppressor cells (MSCs) and regulatory T cells (T-regs) Whether there is a direct interaction between the cells is unclear. As early as the 1980s, it was found that cancer patients and tumor-bearing mice accumulate MSCs