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我院对196例重症肺炎患儿进行分组治疗、对照观察其疗效情况如下。1.临床资料按中华儿科杂志1983;21:32“小儿呼吸道疾病会议纪要”的诊断标准,将确诊为重症肺炎的196例患儿进行分组;98例采用“联合疗法”(称治疗组),另98例用“普通疗法”(称对照组)。两组平均年龄均在2.8～1.2岁;且两组一般情况均无显著差异。2.治疗方法治疗组:在应用抗生素基础上加用“联合疗法”(654-2+雾化吸入+氧疗);用量①654-20.5mg～0.8mg/kg/次入壶。无循环衰竭者1日2次,有循环衰竭者15分种1次至病情改善后每日2次,维持24小时停药。②雾化吸入:抗生素+异丙肾上腺素0.3mg～0.5mg,嗽必平2～4mg或痰易净1～2mg加蒸馏水20ml,用雾化器进行热雾化吸入,每日2～3次直到肺部罗音消失停用。③氧疗:氧流量1～4升/分(浓度22～50％),单侧鼻导管法,间歇6小时1次,每次1小时,至肺部罗音基本吸收停止。对照组用“普通疗法”:抗生素+激素+病毒唑静脉点滴。常规量,1日1次,口服止咬平喘药。两组均以10天为1疗程,观察其治疗结果。3.治疗结果治愈率:治疗组91.8％,对照组61％(P<0.05);死亡率:治疗组3％,对照组10％(P<0.05)。从上述结果看,治疗组明显优越于对照组。4.讨论“联合疗法”主要优点是改善肺微循环,扩张支气管,保护粘膜,杀菌,稀释痰液,?
196 cases of severe pneumonia in our hospital for group therapy, control the efficacy of the situation as follows. 1. Clinical data 196 cases of children diagnosed with severe pneumonia were grouped according to the diagnostic criteria of Pediatric Respiratory Diseases Meeting Minutes 1983; 21: 32; and 98 cases were treated with “combination therapy” (treatment group) Another 98 cases with “general therapy” (called the control group). The average age of the two groups were 2.8 to 1.2 years old; and no significant difference between the two groups in general. 2. Treatment group: In the application of antibiotics based on the use of “combination therapy” (654-2 + inhalation of oxygen therapy); Amount ①654-20.5mg ~ 0.8mg / kg / time into the pot. No circulation failure 2 times a day, there are 15 cases of circulatory failure 1 times to improve the condition 2 times a day, maintaining a 24-hour withdrawal. ② atomization inhalation: antibiotics + isoproterenol 0.3mg ~ 0.5mg, cough Bi Ping 2 ~ 4mg or phlegm easy to clean 1 ~ 2mg plus distilled water 20ml, with a nebulizer thermal atomization inhalation, 2 to 3 times a day Until the lung rales disappear disabled. ③ oxygen therapy: oxygen flow rate of 1 to 4 liters / min (concentration 22 ~ 50%), unilateral nasal catheter method, intermittent 6 hours 1 time, every 1 hour until the pulmonary rales basic absorption stopped. The control group with “common therapy”: antibiotics + hormone + ribavirin intravenous drip. Conventional amount, once a day, oral anti-bite and antiasthmatic drugs. Both groups took 10 days as a course of treatment to observe the treatment results. The cure rate was 91.8% in the treatment group and 61% in the control group (P <0.05). The mortality rate was 3% in the treatment group and 10% in the control group (P <0.05). From the above results, the treatment group was significantly superior to the control group. 4. Discussion “The main advantage of” combination therapy "is to improve pulmonary microcirculation, bronchial expansion, mucosal protection, sterilization, diluted sputum?