Protective role of metallothionein （Ⅰ／Ⅱ） against pathological damage and apoptosis induced by dimeth

• 作 者: GuangJia Yi-QunGu Kung-TungChe
• 机 构: DepartmentofOccupationalandEnvironmentalHealthSciences,DepartmentofPathology,DepartmentofGeneralEduc
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2004年1期
• 关键词: 金属硫因 二甲胂酸 细胞凋亡 病理形态学 细胞毒性

AIM: To better clarify the main target organs of dimethylarsinic acid toxicity and the role of metallothionein (MTs) in modifying dimethylarsinic acid (DMAA) toxicity. METHODS: MT-Ⅰ/Ⅱ null (MT^-/-) mice and the corresponding wild-type mice (MT^+/+), six i