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智利北部安多法加斯大城区由于地质原因引起公共饮用水砷污染,1955～1970年水中砷平均含量为0.5980 ppm,1970年水过滤处理后砷含量降低到0.0815 ppm。居民因饮用砷污染的饮用水后,陆续发生470例慢性砷性皮肤病患者,其中有5例儿童(男2例、女3例)平均年龄为5.3岁,有3例患手指坏疽,2例患足趾坏疽。对4例患慢性砷中毒死亡病例进行尸检,显示中、小动脉内膜纤维增生,并有严重管腔闭塞。本文研究了动脉病,包括心肌梗塞及心脏肥大与儿童、青壮年摄入砷后所引起疾病的关系。
As a result of geological causes of arsenic pollution of public drinking water due to geological reasons, the average concentration of arsenic in water from 1955 to 1970 was 0.5980 ppm. In 1970, the arsenic content of water filtration decreased to 0.0815 ppm. 470 residents of chronic arsenic dermatitis, one in 5 children (2 males and 3 females) with an average age of 5.3 years, were exposed to drinking water contaminated with arsenic. 3 patients had finger gangrene and 2 Suffering from toe gangrene. Autopsy was performed on 4 deaths caused by chronic arsenic poisoning, which showed that the medium and small arterial intimal fibrosis were hyperplastic and had severe lumen occlusion. This article studies the relationship between arterial disease, including myocardial infarction and cardiac hypertrophy, and the disease caused by young children and young adults.