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作者对48例不能一期切除的原发性巨块型肝癌进行多途径的综合治疗。在一期探查术中应用肝动脉结扎、碘化油化疗药物(MDF)混合液灌注化疗和液态硅胶(TH)栓塞术;术后行肝动脉、门静脉分期灌注化疗;化疗间期经皮向癌灶内分点注射无水酒精。综合治疗半年复查结果:PR66.7%、MR22.9%、SD10.4%。复查后依据病情施行Ⅱ期手术切除23例,占本组病例的47.9%(23/48)。本组病例随访结果:6、8、10个月、1、3、5年生存率分别为93.8%、87.5%、79.2%、75.0%、56.1%、25.9%。结果显示,多途径综合治疗疗效显著。
The authors performed multimodal approaches for the treatment of 48 cases of primary massive hepatocellular carcinoma that could not be resectioned. Hepatic arterial ligation, mixed fluid infusion chemotherapy with iodinated oil chemotherapy (MDF) and liquid silicone embolization (TH) were performed during the first phase of exploration. Hepatic artery and portal vein staging chemotherapy was performed after operation; Intravenous injection of absolute alcohol in the stove. Six months of comprehensive treatment results: PR66.7%, MR22.9%, SD 10.4%. After reexamination, 23 cases were performed with stage II surgical resection according to the disease condition, accounting for 47.9% (23/48) of this group of cases. The follow-up results of this group of patients: 6, 8, 10 months, 1, 3, and 5-year survival rates were 93.8%, 87.5%, 79.2%, 75.0%, 56.1%, 25, respectively. .9%. The results showed that the efficacy of multi-path comprehensive treatment was significant.