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目的研究在治疗妊娠期细菌性阴道病患者时,联合使用口服维生素D的方法进行治疗,比较治疗效果,探讨维生素D口服联合维生素C、乳酸杆菌制剂阴道用药在治疗妊娠期细菌性阴道病中有效性。方法 2013年1—12月入院治疗的处于妊娠期的细菌性阴道病患者共有275例,从中选取符合本该文研究条件的妊娠期患者100例作为研究对象。将这100例患者随机分为二组,即对照组和观察组。对于对照组的患者采用维生素C、乳酸杆菌制剂阴道用药的方法进行治疗;对于观察组的患者采用维生素D口服联合维生素C、乳酸杆菌制剂阴道用药的方法进行治疗。在二组患者治疗1周后,对二组患者的治疗效果进行统计对比,主要包括阴道pH值,白带常规及BV检测,血清维生素D检测,症状改善等。在患者治愈停药后1周以及1个月后,对二组患者的细菌性阴道病的复发率进行统计对比,总结维生素D的使用效果。结果经过1周的治疗后,对照组有41例患者治疗有效,观察组有47例治疗有效。停药1周后,对照组复发的患者有7例,观察组有1例复发。二组的治疗结果差异有统计学意义(P<0.05)。结论采用维生素D口服联合维生素C、乳酸杆菌制剂阴道用药的方法,在治疗妊娠期细菌性阴道病的应用中,治疗效果好,减少了复发率,减轻了患者的经济负担,值得在妇科疾病治疗中广泛的推广应用。
Objective To study the treatment of bacterial vaginosis during pregnancy, the combined use of oral vitamin D for treatment, to compare the therapeutic effect of vitamin D oral administration of vitamin C, lactobacillus vaginal preparations in the treatment of bacterial vaginosis during pregnancy effective Sex. Methods A total of 275 bacterial vaginosis patients admitted to hospital from January to December 2013 were enrolled in this study. 100 pregnant women who were eligible for this study were selected as study subjects. The 100 patients were randomly divided into two groups, the control group and the observation group. Patients in the control group were treated with vitamin C and lactobacillus vaginal preparations. Patients in the observation group were treated with oral administration of vitamin D and vitamin C and lactic acid bacteria vaginally. One week after the two groups of patients were treated, the therapeutic effect of the two groups of patients were statistically compared, including vaginal pH value, vaginal discharge routine and BV test, serum vitamin D test, and symptom improvement. One week after the patient was cured and one month after discontinuation, the recurrence rates of bacterial vaginosis in the two groups were statistically compared to summarize the effect of vitamin D administration. Results After a week of treatment, 41 patients in the control group were treated effectively, 47 patients in the observation group were effective. One week after discontinuation, 7 patients relapsed in the control group and 1 patient relapsed in the observation group. The difference between the two groups was statistically significant (P <0.05). Conclusion With vitamin D oral administration of vitamin C and lactic acid bacteria vaginal preparations in the treatment of bacterial vaginosis during pregnancy, the treatment effect is good, reducing the recurrence rate and reduce the financial burden on patients, it is worth the treatment of gynecological diseases In a wide range of applications.