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目的对比经耻骨后前列腺癌根治术与腹腔镜前列腺癌根治术治疗早期局限性前列腺癌的临床疗效。方法抽取2013年1月—2015年11月安阳市第三人民医院86例早期局限性前列腺癌患者,根据不同术式分组,各43例。A组行腹腔镜前列腺癌根治术,B组行经耻骨后前列腺癌根治术。对比两组手术相关指标、术后恢复情况、并发症发生率,随访1年,统计两组生化复发率及完全尿控率。结果 A组术中出血量少,胃肠功能恢复及住院时间短于B组,差异有统计学意义(P<0.05);A组并发症发生率4.65%(2/43)低于B组23.26%(10/43),差异有统计学意义(P<0.05);A组1年后生化复发率11.63%(5/43)、完全尿控率88.37%(38/43)与B组[生化复发率9.30%(4/43)、完全尿控率93.02%(40/43)]比较差异无统计学意义(P>0.05)。结论腹腔镜前列腺癌根治术与经耻骨后前列腺癌根治术治疗早期局限性前列腺癌疗效相当,但前者对机损伤伤小、并发症少,利于术后早期康复。
Objective To compare the clinical effects of radical prostatectomy with laparoscopic radical prostatectomy for the treatment of early localized prostate cancer. Methods Totally 86 patients with early-stage localized prostate cancer in Anyang Third People’s Hospital from January 2013 to November 2015 were selected and grouped according to different surgical procedures, with 43 cases in each group. Group A was treated by laparoscopic radical prostatectomy and Group B by radical retropubic prostatectomy. The two groups of surgery-related indicators, postoperative recovery, the incidence of complications, followed up for 1 year, statistical biochemical recurrence rate and complete urinary control rate. Results The intraoperative blood loss, gastrointestinal function recovery and hospital stay in group A were shorter than those in group B (P <0.05). The incidence of complications in group A was lower (4.65%, 2/43) than that in group B (P <0.05); The biochemical recurrence rate was 11.63% (5/43) in group A and 88.37% (38/43) in group A Recurrence rate was 9.30% (4/43), complete urinary control rate was 93.02% (40/43)]. There was no significant difference between the two groups (P> 0.05). Conclusions Laparoscopic radical prostatectomy is equivalent to radical prostatectomy for the treatment of early-stage localized prostate cancer. However, the former is less invasive and has fewer complications, which will benefit the early rehabilitation.