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本文评价了尼卡地平在冠状动脉疾病中的短期抗心绞痛血流动力学作用。 15例男性冠状动脉疾病患者,平均年龄56岁。先于一分钟内静滴尼卡地平2mg,然后持续静滴每分钟50μg,使收缩压下降1.3～2.7 kPa。结果表明,静息状态下静滴尼卡地平后,心率加快(每分钟69±3至81±3次/L),全身血管阻力降低(自1183±70至733±33dynes·sec·cm~(-5)),左心室舒张终末压仍恒定在1.9±0.13 kPa,每搏血量自每分钟102±9增至143±13 ml,冠状动脉阻力自每分钟
This article evaluates the short-term anti-anginal hemodynamic effects of nicardipine in coronary artery disease. 15 patients with coronary artery disease, the average age of 56 years old. First intravenous infusion of nicardipine 2mg within one minute, and then intravenous infusion of 50μg per minute, the systolic blood pressure decreased 1.3 ~ 2.7kPa. The results showed that heart rate increased (69 ± 3 to 81 ± 3 times / L per minute) and systemic vascular resistance decreased (from 1183 ± 70 to 733 ± 33 dynes · sec · cm ~ (-1)) after intravenous nicardipine intravenously -5)), left ventricular end diastolic pressure was still constant at 1.9 ± 0.13 kPa, stroke volume from 102 ± 9 per minute to 143 ± 13 ml, coronary resistance from every minute