论文部分内容阅读
武汉地区肺结核短程化疗开始于70年代中期,80年代进行了大量的临床观察。为了进一步发挥短程化疗在控制结核病方面的作用,中国防痨协会武汉分会、中华医学会武汉分会呼吸、结核学会于1987年7月10日联合召开了肺结核短程化疗座谈会。会议由段生福、李晖教授主持,28个医疗单位的代表参加,现将讨论情况综合整理如下。一、短程化疗是结核病防治工作的实际需要郑燕春医师(武汉市结核病防治所):在结核病化疗实践中发现,临床试验菌阳肺结核病人长程标化疗效痰菌阴转率可达90％以上,复发率10％以下;而临床应用中实际疗效痰菌阴转率在90％以下,复发率在10％以上,主要原因是疗程长,病人不规律用药,结果产生一些难治病例及社会传染源。由INH、SM及PAS或TB_1组成的长程标化方案,虽然杀菌作用较强,但灭菌作用较弱。合理的短程化疗方案不仅要求
TB treatment of tuberculosis in Wuhan began in the mid-1970s, and a large number of clinical observations were made in the 1980s. In order to further play the role of short-course chemotherapy in the control of tuberculosis, Chinese antituberculosis Association Wuhan Branch, Chinese Medical Association of Wuhan Branch of Respiratory, Tuberculosis Association on July 10, 1987 jointly held a forum on tuberculosis short-course chemotherapy. The meeting was presided over by Duan Shengfu and Li Hui and representatives of 28 medical units attended the meeting. The discussions are summarized as follows. First, the short-range chemotherapy is the actual needs of tuberculosis prevention and treatment Dr. Zheng Yanchun (Wuhan TB Control Institute): In the practice of tuberculosis chemotherapy found that clinical trials of bacteria positive pulmonary tuberculosis long-term standard efficacy sputum negative conversion rate of up to 90%, relapse Rate of 10% or less; while the clinical application of the actual efficacy of sputum negative conversion rate of 90% or less, the recurrence rate of 10% or more, mainly due to long course of treatment, patients with irregular medication, resulting in some refractory cases and social sources of infection. The long-range standardization scheme consisting of INH, SM and PAS or TB_1, although bactericidal effect is strong, but sterilization is weak. Reasonable short-course chemotherapy regimens not only required