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目的寻求治疗结核包囊性胸腔积液的新方法。方法胸膜活检确诊为结核性胸腔积液并经B超或胸部X线证实有粘连包囊的病人15例,经胸腔内注入尿激酶每次10万单位,用60ml生理盐水稀释,每8~12h重复,连续5次,每次记录抽取胸水总量,并复查B超观察粘连包囊情况。对照组为单纯用抗结核治疗及间断抽胸水15例。结果实验组13例有效,总有效率86.7%。对照组2例有效,有效率13.3%,疗效明显优于对照组(P<0.05)。结论尿激酶胸腔内注入是治疗结核性粘连包囊性胸腔积液的一种安全可靠的新方法。
Objective To seek a new method for the treatment of tuberculous pleural effusion. Methods Fifteen patients with tuberculous pleural effusion diagnosed by pleural biopsy and with cystic adhesions confirmed by ultrasound or chest radiography were injected with 10 000 units of urokinase through the thoracic cavity and diluted with 60 ml normal saline every 8 to 12 hours Repeat, 5 times in a row, the total volume of pleural effusion extracted from each record, and review B ultrasound observation of adhesions cysts. Control group was treated with anti-tuberculosis and intermittent pleural effusion in 15 cases. Results In the experimental group, 13 cases were effective and the total effective rate was 86.7%. Two cases in the control group were effective and the effective rate was 13.3%. The curative effect was obviously superior to the control group (P <0.05). Conclusion Thoracic injection of urokinase is a safe and reliable new method for the treatment of tuberculous adhesive cystic pleural effusion.