The Effect of 5-Azacytidine (5-Aza-CR) And Its Analogue on Cell Differentiation and DNA Methylation

• 作 者: 何忠效 饶泓
• 机 构: DepartmentofBiology,BeijingNormalUniversity,NationalLaboratoryofBiomacromolecule,Beijing100875,PRC,P
• 出 处: Science in China,Ser.B
• 发表日期: 1993年4期
• 关键词: Methylation methylation DNA deoxycytidine Polymerase RNA donor stain inhibited a

The effect of 5-aza-CR and 5-aza-2’-deoxycytidine(5-aza-CdR)on cell differentiation and DNA methylation of HL-60 cells was studied. The differentiation index of HL-60 cells was measured after being treated with drugs by using the NBT stain method. DNA met