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本文用肝血管瘤石蜡切片作血管内皮生长因子（ＶＥＧＦ）链霉亲和素—生物素—过氧化物酶免疫组织化学染色（即ＳＡＢＣ法）和核仁组成区相关嗜银蛋白（ＡｇＮＯＲ）计数方法，研究ＶＥＧＦ在肝血管瘤成因中的地位。结果显示：４８例肝血管瘤标本中，ＶＥＧＦ阳性表达率为７５．０％，其中（＋）者９例，（）者１１例，（）者１６例，且ＶＥＧＦ表达强度在不同的组别间ＡｇＮＯＲ计数差异显著（Ｐ＜０．０１）。提示ＶＥＧＦ在肝血管瘤的成因中可能具有重要意义。
In this paper, hepatic hemangioma paraffin sections were used for the determination of vascular endothelial growth factor (VEGF) streptavidin-biotin-peroxidase immunohistochemical staining (SABC method) and nucleolar organizer region-related AgNOR count Methods to study the role of VEGF in the genesis of hepatic hemangiomas. The results showed that in 48 specimens of hepatic hemangiomas, the positive expression rate of VEGF was 75.0%, of which 9 were (+), 11 were (), 16 were (), and the expression of VEGF was different There was significant difference in AgNOR count between groups (P <0.01). Tip VEGF in the genesis of hepatic hemangioma may be of great significance.