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目的:评价阿卡波糖辅助治疗社区糖尿病的疗效。方法:2014年6月~2016年5月,筛选2型糖尿病患者94例,采用随机数字表达法分组,双盲研究,对照组、观察组各入组47例。均安排胰岛素等常规药物治疗,对照组、观察组分别联合安慰剂、阿卡波糖,持续6个月。结果:治疗后,组内对比,观察组与对照组Hb A1c、FBG、PBG2h低于治疗前,组间对比观察组低于对照组,观察组BMI低于治疗前、对照组,差异有统计学意义(P<0.05)。观察组出现1例腹泻,对照组未见不良反应。结论:阿卡波糖治疗2型糖尿病,有助于血糖、体重控制。
Objective: To evaluate the efficacy of acarbose adjuvant treatment of community diabetes mellitus. Methods: From June 2014 to May 2016, 94 patients with type 2 diabetes mellitus were screened. Randomized numerical methods were used to divide the patients into two groups. The control group and the observation group were enrolled in each group. Both groups were given insulin and other conventional drug treatment, control group, observation group were combined with placebo, acarbose, for 6 months. Results: After treatment, the levels of Hb A1c, FBG and PBG2h in the observation group and the control group were lower than those in the control group before and after treatment, and the BMI in the observation group was lower than that of the control group before and after treatment Significance (P <0.05). One case of diarrhea occurred in observation group and no adverse reaction in control group. Conclusion: Acarbose treatment of type 2 diabetes, contribute to blood sugar, weight control.