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在各种并发血栓栓塞的疾病时,使用抗凝血疗法的价值,已无容置疑。但对制剂的选择和剂量的确定,意见仍不一致。例如对肝素的适应症、剂量、服药间隔以及与其他抗凝剂的并用等问题,各家看法迥异。我们认为,对肺梗塞和周围动脉栓塞病人,使用肝素是适宜的;而在心肌梗死,特别是当存在有广泛的心肌病变时,则禁用肝素。因为凝血作用的骤烈降低,在一定程度上妨碍了梗死区的愈合,从而增加了心肌破裂的危险性。在肺梗塞或周围动脉栓塞病人,肝素第一次静脉注射剂量为10000单位。以后每4小时注射5000单位。在每次注射前测定凝血时间。如
In a variety of diseases associated with thromboembolism, the value of using anticoagulant therapy has been beyond doubt. However, the formulation of choice and dose determination, the views are still inconsistent. For example, the indications for heparin, dosage, medication interval and other anticoagulants and other issues, different views. In our opinion, the use of heparin is appropriate for patients with pulmonary infarction and peripheral arterial embolism, and heparin is disabled during myocardial infarction, especially when extensive cardiomyopathy is present. Because of the sharp reduction in coagulation, to a certain extent, hinder the healing of infarct area, thereby increasing the risk of myocardial rupture. In pulmonary infarction or peripheral arterial embolism patients, the first intravenous injection of heparin dose of 10,000 units. 5000 units will be injected every 4 hours thereafter. The clotting time was measured before each injection. Such as