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目的了解某口腔医院特殊使用级抗菌药物应用现状,促进特殊使用级抗菌药物的合理使用。方法采用回顾性统计方法,对2013-2015年该院特殊使用级抗菌药物使用情况进行统计、分析。结果 2013-2015年,该院门急诊未使用特殊使用级抗菌药物。住院患者特殊使用级抗菌药物DDDs占比分别为0.77%、0.41%和0.51%,金额占比分别为4.02%、2.45%和2.28%,使用强度(每日每百张床位消耗抗菌药物的DDDs)分别为0.27、0.16和0.19,使用率分别为0.25%、0.15%和0.19%;接受特殊使用级抗菌药物治疗住院患者微生物送检率分别为93.33%、80.00%和92.31%。注射用美罗培南和注射用盐酸万古霉素的DDDs占比在2013-2015年中均分别位居第1位和第2位。结论该院特殊使用级抗菌药物2013-2015年中均使用极少,应用较为严格,使用品种符合口腔颌面部感染的抗菌治疗特点。
Objective To understand the application status of special-use antimicrobials in a stomatological hospital and promote the rational use of special-use antibacterials. Methods A retrospective statistical method was used to analyze and analyze the use of special-use antimicrobials in this hospital during 2013-2015. Results From 2013 to 2015, there was no special use-level antimicrobial agent in the department emergency department. DDDs accounted for 0.77%, 0.41% and 0.51%, respectively, accounting for 4.02%, 2.45% and 2.28%, respectively, and the intensity of use (daily DDDs consumption of antibacterials per 100 beds) 0.27, 0.16 and 0.19, respectively. The rates of use were 0.25%, 0.15% and 0.19% respectively. The rates of microbe inpatients receiving special grade antibacterials were 93.33%, 80.00% and 92.31% respectively. The DDDs of meropenem for injection and vancomycin hydrochloride for injection were ranked No. 1 and No. 2 respectively in 2013-2015. CONCLUSIONS The grade of antibacterials for special use in this hospital are rarely used in 2013-2015, and their applications are more stringent. The varieties used meet the antibacterial treatment characteristics of oral and maxillofacial infections.