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院内下呼吸道感染是最常见的医院内感染之一,其发生率和病死率很高,已引起医学界的极大关注.本文通过对70例院内下呼吸道感染患者进行病原学及细菌耐药分析,旨在更准确地指导抗生素的应用.1 实验过程和方法1.1 研究对象 参照1990年院内获得性支气管-肺感染试行标准及原有慢性肺疾病的院内下呼吸道感染的诊断标准.从1994～1996年两年间选出符合条件的70例无纤维支气管镜(纤支镜)禁忌的院内下呼吸道感染患者作为研究对象.其中男41例,女29例.年龄22～78岁,平均年龄56岁.所有患者均有一种以上基础疾病,其中慢性肺疾病45例,恶性肿瘤12例,结缔组织病及应用类固醇激素者7例,机械通气者4例,糖尿病2例.70例患者平均体温为38.4℃(范围在36.8～39.5℃),平均WBC为15.O×10~9/L(范围6.1～47)×10~9/L).66例患者在进行纤支镜检查前均用过一种以上抗生素治疗.
Nosocomial lower respiratory tract infection is one of the most common nosocomial infections and its incidence and mortality rate have drawn great attention from the medical community.Through the analysis of 70 cases of nosocomial lower respiratory tract infection in patients with etiological and bacterial resistance analysis , Aimed at more accurate guidance on the application of antibiotics.1 Experimental process and method 1.1 The object of reference with reference to the standard of hospital acquired bronchitis-lung infection in 1990 and the original diagnosis of chronic pulmonary disease hospital nosocomial lower respiratory tract infection.From 1994 to 1996 A total of 70 patients with nosocomial lower respiratory tract infection were selected as the eligible patients under the age of 70 in the two years, 41 were males and 29 were females, aged from 22 to 78 years with a mean age of 56 years. All patients had more than one type of underlying disease, including 45 cases of chronic lung disease, 12 cases of malignant tumor, connective tissue disease and steroid hormone in 7 cases, 4 cases of mechanical ventilation, 2 cases of diabetes .70 patients with an average body temperature of 38.4 ℃ (Ranging from 36.8 ° C to 39.5 ° C) with an average WBC of 15.O x 10-9 / L (range, 6.1-47) x 10-9 / L) .66 patients underwent one The above antibiotic treatment.