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目的探讨丁苯酞氯化钠治疗急性缺血性脑卒中的临床疗效。方法回顾性分析自2013年10月至2014年10月收治的108例急性缺血性脑卒中患者的临床资料。按照随机数字表法分为观察组和对照组两组,每组均有54例患者。对照组患者口服阿司匹林和静脉滴注胞二磷胆碱,观察组在对照组的基础上采用丁苯酞氯化钠注射液治疗。0.5个月后观察两组急性脑卒中患者的神经功能缺损评分(NIHSS评分)和临床效果。结果两组患者在治疗前后的NIHSS评分和治疗后的临床效果差异均有统计学意义(P<0.05),且观察组治疗效果优于对照组(P<0.05)。结论丁苯酞氯化钠注射液治疗急性缺血性脑卒中临床疗效好,值得在临床上推广使用。
Objective To investigate the clinical efficacy of butylphthalide and sodium chloride in the treatment of acute ischemic stroke. Methods The clinical data of 108 patients with acute ischemic stroke admitted from October 2013 to October 2014 were retrospectively analyzed. According to random number table divided into observation group and control group two groups, each group has 54 patients. Patients in the control group received oral aspirin and intravenous citicoline. The observation group was treated with sodium butyrate and sodium chloride injection on the basis of the control group. After 0.5 months, the neurological deficit score (NIHSS score) and clinical effect in two groups of acute stroke patients were observed. Results The NIHSS scores of the two groups before and after treatment were significantly different from those after treatment (P <0.05), and the therapeutic effect of the observation group was better than that of the control group (P <0.05). Conclusion Butylphthalide sodium chloride injection in the treatment of acute ischemic stroke clinical efficacy is good, it is worth promoting in clinical use.