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迄今为止,治疗常现丝虫病的主要药物仍然是海群生。但它的疗效差,而且副作用多。作者在瑞典用甲苯咪唑治疗9例常现丝虫病患者,其中6例曾用海群生治疗无效。给药途径均为口服,剂量为每次100mg,每天2次,连续服用30天,其中1例患者给予2个疗程,另2例患者则连续给药7周。结果,除1例6岁儿童由于严重的副反应而中止治疗外,8例中7例患者的微丝蚴均已消失。1例经2个疗程治疗后,仅查见少量微丝蚴。此外,大多数病人的血液嗜酸粒细胞计数均显著降低。在治疗中,除1例患者出现高热和
So far, the main drug for the treatment of filariasis is still seaquot. But its curative effect is poor, and the side effects are many. The authors used mebendazole in Sweden to treat 9 patients with filariasis, of whom 6 had been treated with seaquot. The route of administration was oral, the dose of 100mg twice daily for 30 days, of which 1 patients were given two courses of treatment, while the other two patients were given for 7 weeks. As a result, all of the seven patients in eight of the eight patients had their microfilaria disappeared, except one of the 6-year-old children whose treatment was discontinued due to severe side effects. One case after 2 courses of treatment, only see a small amount of microfilariae. In addition, blood eosinophil counts were significantly lower in most patients. In the treatment, except one case of fever and fever