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目的 观察局限期小细胞肺癌(SCLC)综合治疗的疗效及毒副反应。方法 对34例局限SCLC采用放化疗结合,先接受二个周期EP方案化疗后,再放疗50~60Gy/5.5~6周,照射野包括原发灶同侧肺门、相应纵隔双锁骨上及下颈部,放疗结束后继续化疗。结果 全组CR52. 9%、PR53. 3%,总有效率88 .2%,1、2年生存率分别为52 .9%、32.. 4%。结论 对局限期SCLC采用放化疗结合优于以往的单纯化疗或放疗。
Objective To observe the curative effect and side effects of combined therapy of limited stage small cell lung cancer (SCLC). Methods 34 patients with localized SCLC were treated with radiotherapy and chemotherapy. The patients were treated with two cycles of EP regimen followed by 50-60 Gy / 5.5-6 weeks of radiotherapy. The radiation field included the ipsilateral hilar of the primary tumor, the corresponding supraclavicular double supraclavicular Neck, chemotherapy after the end of chemotherapy. Results The overall CR52.9%, PR53.3%, the total effective rate 88.2%, 1, 2-year survival rates were 52.9%, 32 .. 4%. Conclusions Chemotherapy and chemotherapy combined with chemotherapy in advanced stage SCLC is superior to the conventional chemotherapy or radiotherapy alone.