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目的探讨奥硝唑在治疗急性根尖周炎时的临床疗效。方法将90例急性根尖周炎患者随机平均分为3组,第1组为治疗组,予奥硝唑静脉滴注,0.5 g/次,1次/d,连用3 d;第2组予甲硝唑静脉滴注,1.0 g/次,1次/d,连用3 d;第3组不用药,3 d后观察临床疗效并比较。结果第1组总有效率73.33%,第2组总有效率46.67%,第3组总有效率16.67%,经两两统计学检验,均有显著差异(P<0.05)。结论奥硝唑作为新一代抗厌氧菌药物,在治疗急性根尖周炎时具有显著临床疗效,值得推广。
Objective To investigate the clinical efficacy of ornidazole in the treatment of acute periodontitis. Methods Ninety patients with acute periodontitis were divided into three groups randomly. The first group was treated with ornidazole by intravenous drip, 0.5 g once daily for 3 days. The second group Metronidazole intravenous infusion, 1.0 g / time, 1 / d, once every 3 d; the third group without medication, 3 d after the observation of clinical efficacy and comparison. Results The total effective rate in group 1 was 73.33%, the total effective rate in group 2 was 46.67%, the total effective rate in group 3 was 16.67%. Significant differences were found between the two groups (P <0.05). Conclusion Ornidazole as a new generation of anti-anaerobic drugs in the treatment of acute apical perioditis has a significant clinical effect, it is worth promoting.