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本文比较了两组成人急性粒细胞型白血病(急粒)治疗结果以评价缓解期给予中等强度的化疗对预后的影响。多数病人诱导化疗采用以下方案:阿糖胞甙(Ara-C)10mg/kg 输注24小时,紧接着注射正定霉素(DM)1.5 mg/kg,24小时后注射阿霉素1.5mg/kg。2周后重复上述方案,再2周后给 Ara-C 2mg/kg/日和6-硫鸟嘌呤(6TG)2mg/kg/日3个短疗程,分别为3、4、5日,各疗程间隔5日。最后4例头2疗程给3药并用的较强烈的化疗。两组病例缓解率相同(60%)。获得缓解后,所有病人均每周1次给
This article compares the outcomes of two adult acute myeloid leukemias (acute pellets) to evaluate the effect of moderate-intensity chemotherapy on prognosis in the remission period. Most patients underwent induction chemotherapy with the following regimen: Ara-C 10 mg / kg infusion for 24 hours, followed by injection of 1.5 mg / kg daunorubicin (DM), and 24 hours after injection of doxorubicin 1.5 mg / kg . After 2 weeks, the above protocol was repeated. After 2 weeks, 3 short courses of Ara-C 2mg / kg / day and 6-thioguanine (6TG) 2mg / kg / day were given for 3, 4 and 5 days respectively. Interval of 5 days. The last 4 cases of the first two courses to 3 drugs and the use of more intense chemotherapy. The two groups of patients with the same rate of response (60%). After remission, all patients were given once a week