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利用ILO92耳动态分析仪,测试23例(46耳)正常青年人的畸变产物耳声发射(DPOAE)和对侧窄带噪声(NBN)的影响。结果:①对测NBN对DPOAE的抑制非常明显,随NBN强度增加DPOAE幅值下降增加,二者呈显著负相关(F2为1~6kHZ,γ为-0.49~-0.24,均P<0.05,斜率为0.26~0.08dB/10dB)。②在F2为中频(1,2kHZ)且为中等强度(45~65dBSPL)时,抑制效应最大。DPOAE及其抑制效应出现率最高(100%)。③对侧NBN在中等强度(50dBHL)以下,抑制效应有频率特异性,且可引起最大抑制效应。最大抑制可达3.85dB。④在对侧耳给予低~中等强度(20~50dBHL)NBN时,同侧耳的噪声底不变,因此可排除中耳声反射和经颅传导的影响。并讨论了对侧抑制效应的生理机理。认为DPOAE对侧抑制效应的测试,是研究内侧橄榄耳蜗系统对耳蜗功能调控作用的快速敏感、简单无创、客观可靠的方法。
The effect of distortion product otoacoustic emissions (DPOAE) and contralateral narrowband noise (NBN) in 23 normal (46early) young adults was tested using an ILO92 ear dynamic analyzer. Results: (1) NBN inhibited the DPOAE significantly, and the amplitude of DPOAE decreased with the increase of NBN intensity. There was a significant negative correlation between DPOAE amplitude and the NBN intensity (F2 was 1 ~ 6kHZ, γ was -0.49 ~ -0.24, both P <0.05, slope 0.26 ~ 0.08dB / 10dB). ② When F2 is medium frequency (1, 2kHZ) and medium intensity (45 ~ 65dBSPL), the inhibition effect is the largest. DPOAE and its inhibitory effect appeared the highest (100%). ③ contralateral NBN below the medium intensity (50dBHL), the inhibitory effect of frequency-specific, and can cause maximum inhibitory effect. The maximum inhibition of up to 3.85dB. ④ In the contralateral ear to give low to moderate intensity (20 ~ 50dBHL) NBN, the ipsilateral ear noise floor unchanged, it can exclude the middle ear acoustic reflex and transcranial conduction. The physiological mechanism of contralateral inhibition was also discussed. It is believed that the DPOAE contralateral inhibitory effect test is a fast and sensitive, simple and non-invasive, objective and reliable method for studying the regulation of the cochlear function of the medial olivocochlear system.