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目的探讨职业人群中消化性溃疡(PU)发病的危险因素及其风险度,为职业人群PU的预防提供依据。方法从该企业职业人群中随机抽取9 463例职工,以其中明确诊断为PU的363例职工为病例组,通过成组匹配,选择与病例组均衡可比的400例健康人为对照组,采用同一调查表进行面对面访谈。按年龄分层进行分层分析和交互作用分析。结果男性、吸烟、接触粉尘、饮酒和干硬饮食是PU发生的独立危险因素(OR=1.411~2.485,P<0.05),它们的病因分值分别为0.421、0.318、0.243、0.188、0.093。危险因素两两交互作用分析,男性与吸烟、男性和饮酒、吸烟和干硬饮食、男性和干硬饮食的交互作用指数分别为0.313、0.186、0.063和0.015。结论男性、吸烟、粉尘暴露、饮酒和干硬饮食是职业人群中PU发病的独立危险因素,两两因素间无明显的协同作用。
Objective To explore the risk factors and risk of peptic ulcer (PU) in occupational population and provide the basis for prevention of PU in occupational population. Methods A total of 9 463 workers were selected from the occupational population of the enterprise. A total of 363 workers diagnosed as PU in this group were selected as the case group. By means of group matching, 400 healthy people with balanced group were selected as the control group. Table for face-to-face interviews. Stratified by age stratification analysis and interaction analysis. Results Male, smoking, exposure to dust, alcohol consumption and dry and hard diet were independent risk factors of PU (OR = 1.411-2.485, P <0.05). The etiological scores were 0.421,0.318,0.243,0.188,0.093 respectively. Interaction between risk factors any two, male and smoking, men and drinking, smoking and dry and hard diet, male and dry and hard diet interaction index were 0.313,0.186,0.063 and 0.015. Conclusions Male, smoking, dust exposure, alcohol consumption and dry and hard diet are independent risk factors for PU in occupational population. There is no obvious synergistic effect between two factors.