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TIL 与癌细胞是肿瘤组织中直接对立的两大细胞群体,TIL 基本反映了肿瘤局部的免疫特性。本文着重分析了新鲜的与 IL-2扩增条件下的膀胱癌 TIL 的表型特征和免疫活性,探讨了膀胱癌 TIL 的杀伤机理及其与生物反应调节剂 BCG、OK_(432)的关系。本文认为 TIL 的生物密度可以作为膀胱癌独立的预后指标,对 TIL 的深入研究也必将为膀胱癌的过继治疗开辟更广阔的领域。
TIL and cancer cells are directly opposed to each other in tumor tissue. TIL basically reflects the local immune characteristics of tumor. This article focuses on the analysis of the phenotype and immune activity of bladder cancer TIL under fresh and IL-2 conditions, and explores the mechanism of TIL killing in bladder cancer and its relationship with BCI and OK_ (432). In this paper, the biological density of TIL can be used as an independent prognostic indicator of bladder cancer, further research on TIL will open up a broader field for the treatment of bladder cancer.