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目的观察甘露醇治疗急性自发性脑出血的疗效。方法选择2010年6月—2012年11月我院收治的急性自发性脑出血患者80例,将其随机分为观察组和对照组,各40例。观察组给予甘露醇治疗,对照组给予甘油果糖治疗,观察两组患者颅内出血量、卒中评分及安全性。结果治疗前两组患者卒中评分和颅内出血量比较,差异无统计学意义(P>0.05);治疗后观察组卒中评分高于对照组,颅内出血量低于对照组(P<0.05)。对照组不良反应发生率为12.5%(5/40),与观察组的7.5%(3/40)比较,差异无统计学意义(P>0.05)。结论甘露醇治疗急性自发性脑出血患者效果较好,安全性高,值得推广使用。
Objective To observe the efficacy of mannitol in the treatment of acute cerebral hemorrhage. Methods Eighty patients with acute spontaneous cerebral hemorrhage admitted from June 2010 to November 2012 in our hospital were randomly divided into observation group and control group, 40 cases in each group. Mannitol was given to the observation group and glycerol fructose was given to the control group. Intracranial hemorrhage, stroke score and safety were observed in both groups. Results There was no significant difference in stroke score and intracranial hemorrhage between the two groups before treatment (P> 0.05). After treatment, the score of stroke in observation group was higher than that of control group, and the amount of intracerebral hemorrhage was lower than that of control group (P <0.05). The incidence of adverse reactions in the control group was 12.5% (5/40), which was not significantly different from that in the observation group (7.5%, 3/40) (P> 0.05). Conclusion Mannitol in patients with acute spontaneous cerebral hemorrhage better effect, high safety, it is worth promoting the use of.