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目的探讨放射治疗对骨转移癌患者疼痛的缓解效果。方法蚌埠医学院第一附属医院肿瘤放疗科自2010年8月-2011年7月共收治83例骨转移患者,对83例患者122处骨转移病灶均采用直线加速器6MV-X治疗,随机分成两组,常规分割组(52例73处):给予2 Gy/次,5 d/周,总量40 Gy/4周;大分割组(31例49处):给予3 Gy/次,5d/周,总量30 Gy/2周。结果两组总有效率为90.2%,常规剂量与大剂量分割组有效率分别为91.8%、87.8%,两种不同的剂量分割方式的有效率差异无统计学意义,P>0.05。结论骨转移癌的放射治疗止痛效果既快又好,两种不同剂量分割方法的止痛疗效和副作用相近。
Objective To investigate the effect of radiotherapy on pain relief in patients with bone metastases. Methods Tumor radiotherapy department of the First Affiliated Hospital of Bengbu Medical College from August 2010 to July 2011 treated a total of 83 patients with bone metastases, 83 patients with bone metastases in 122 lesions were treated with a linear accelerator 6MV-X were randomly divided into two Group, the conventional group (52 of 73): given 2 Gy / time, 5 d / week, the total amount of 40 Gy / 4 weeks; large division group (31 cases 49): given 3 Gy / time, , A total of 30 Gy / 2 weeks. Results The total effective rate was 90.2% in both groups. The effective rates were 91.8% and 87.8% for the conventional and high-dose groups, respectively. There was no significant difference in the effective rates between the two different methods (P> 0.05). Conclusion Radiotherapy of bone metastases has a fast and good analgesic effect. The analgesic effects and side effects of the two different dose divisions are similar.