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目的探讨脑膜癌病的临床特点和诊断方法。方法回顾性分析以头痛为首发症状的患者41例,经脑脊液细胞学确诊为脑膜癌病28例,结合文献进行分析。结果经脑脊液细胞学检查发现异形细胞的患者共28例,余13例分别诊断为偏瘫性偏头痛1例,普通偏头痛2例,眼肌麻痹性偏头痛2例,特发性颅内压增高症3例,肌紧张性头痛3例,静脉窦血栓2例。结论脑膜癌病临床表现无特异性,临床上常以头痛起病,反复CSF细胞学检查是确诊的重要手段。
Objective To explore the clinical features and diagnosis of meningeal cancer. Methods Retrospective analysis of 41 patients with headache as the first symptom, cerebrospinal fluid cytology confirmed 28 cases of meningeal cancer, combined with the literature. Results A total of 28 patients with abnormal cells were found by CSF test. One patient was diagnosed as hemiplegia migraine in the remaining 13 patients, 2 migraine in general, 2 as migraine with ophthalmoplegia, and an increase in idiopathic intracranial pressure 3 cases of disease, muscle tension headache in 3 cases, 2 cases of sinus thrombosis. Conclusions The clinical manifestations of meningeal cancer are nonspecific. Headache often starts in clinic and recurrent CSF cytology is an important means of diagnosis.